Symbol
Name
ID

Wdfy3
WD repeat and FYVE domain containing 3
MGI:1096875

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Microcephaly	Intellectual disability
Disease(s) Associated with WDFY3	Microcephaly	Intellectual disability
primary autosomal dominant microcephaly 18

Mouse Phenotypes

increased radial glial cell number

premature neuronal precursor differentiation

abnormal neuronal migration

abnormal neuronal precursor proliferation

abnormal forebrain development

abnormal cortical intermediate zone morphology

abnormal cortical ventricular zone morphology

absent subplate

increased forebrain size

enlarged lateral ventricles

enlarged third ventricle

abnormal cerebral hemisphere morphology

abnormal cerebral cortex morphology

abnormal neocortex morphology

increased neocortex size

abnormal somatosensory cortex morphology

abnormal stratification in cerebral cortex

thin cerebral cortex

small olfactory bulb

abnormal embryonic/fetal subventricular zone morphology

abnormal lateral ganglionic eminence morphology

abnormal medial ganglionic eminence morphology

decreased neuronal precursor cell number

ectopic cortical neuron

Availability

Mouse Genotype

Wdfy3^disc/Wdfy3^disc

Wdfy3^{tm1a(KOMP)Mbp}/Wdfy3^{tm1a(KOMP)Mbp}

Wdfy3^{tm1a(KOMP)Mbp}/Wdfy3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23